G-CSF administration to adult mice stimulates the proliferation of microglia but does not modify the outcome of ischemic injury
Recent evidence suggests that adult bone marrow stem cells reduce tissue damage and promote repair following CNS ischemic injury.Since granulocyte-colony stimulating factor (G-CSF) mobilizes hematopoietic stem cells to the circulating compartment, here we tested whether administration of this drug modifies the outcome of a permanent occlusion of th